Tryp Therapeutics Inc (TRYPF) Corporate Presentation

Corporate Presentation Fall 2021 MILLIONS OF PATIENTS ARE SUFFERING FROM CHRONIC PAIN 10 Existing treatments have limited efficacy and significant side effects for the 4 million individuals in the US who have been diagnosed with fibromyalgia. Fewer than 10% of patients adhere to approved treatments after one year. Nearly 30% of patients take opioids despite the lack of evidence for efficacy and the risk of addiction and/or overdose. More than 1 million people have been diagnosed with phantom limb pain in the United States. Existing treatment methods—such as general pain medication, mirror therapy and acupuncture—are ineffective for many patients. Because this pain is neurological, it is a prime target for treatment with psilocybin. CRPS results from misfiring of pain signals within the brain after an injury, surgery, stroke or heart attack. We estimate that nearly 100,000 people have been diagnosed with CRPS in the United States. Current treatments are ineffective, leaving physicians with few options for suffering patients. Fibromyalgia Phantom Limb Pain CRPS https://pubmed.ncbi.nlm.nih.gov/26755658/ | https://www.jrheum.org/content/early/2017/07/26/jrheum.170098 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0240431 | https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.445.2671&rep=rep1&type=pdf