Tryp Therapeutics Inc (TRYPF) Corporate Presentation

Corporate Presentation Fall 2021 LIVING WITH AN OVEREATING DISORDER CAN FEEL LIKE THERE IS NO END IN SIGHT 12 Hypothalamic Obesity ● BED is characterized by recurring episodes of eating large quantities of food and feeling unable to stop. ● Nearly 30% of people seeking weight loss treatments show signs of BED. ● Up to 3.5% of females and 2.0% of males will develop BED at some point in their lives. ● Hypothalamic obesity, a rare disease, is caused by damage to the hypothalamus, which controls hunger. ● The damage is often caused by surgical removal of a brain tumor. ● This condition can dominate patients’ day-to-day lives, and with no FDA-approved therapies available for the condition, patients have few options. Binge eating disorder We’re very excited for the potential of Tryp’s treatment. The potential impact on patients’ lives is that it would be life changing for them.” “ — Jennifer Miller, Professor, University of Florida https://www.nationaleatingdisorders.org/statistics-research-eating-disorders

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