Tryp Therapeuatics (TRYPF) Coverage Report

RATINGS DISPERSION AND BANKING RELATIONSHIPS AS OF (August 26, 2021) Rating % IB % BUY 80.9 65.3 NEUTRAL 19.1 44.1 SELL 0.0 0.0 COMPANIES UNDER MICHAEL'S COVERAGE Achieve Life Sciences, Inc. (ACHV) Armata Pharmaceuticals, Inc. (ARMP) Artelo Biosciences Inc. (ARTL) Eiger BioPharmaceuticals Inc. (EIGR) 4D Pharma, PLC (LBPS) Intec Pharma Ltd. (NTEC) BiomX Inc. (PHGE) Rhythm Pharmaceuticals Inc. (RYTM) Savara Inc. (SVRA) Viridian Therapeutics Inc. (VRDN) AcelRx Pharmaceuticals Inc. (ACRX) Arch Therapeutics Inc. (ARTH) Catabasis Pharmaceuticals, Inc. (CATB) Forte Biosciences, Inc. (FBRX) Marinus Pharmaceuticals, Inc. (MRNS) Ovid Therapeutics, Inc. (OVID) Palatin Technologies, Inc. (PTN) SCYNEXIS Inc. (SCYX) Tryp Therapeutics, Inc. (TRYPF) Zynerba Pharmaceuticals Inc. (ZYNE) COMPANY SPECIFIC DISCLOSURES Ladenburg Thalmann & Co. Inc received compensation for investment banking services from Tryp Therapeutics, Inc. within the past 12 months. Ladenburg Thalmann & Co. Inc had an investment banking relationship with Tryp Therapeutics, Inc. within the last 12 months. Ladenburg Thalmann & Co Inc. acted in an advisory capacity for Tryp Therapeutics, Inc. in the last 12 months. Ladenburg Thalmann & Co. Inc. makes a market in Rhythm Pharmaceuticals Inc.. OTHER COMPANIES MENTIONED Rhythm Pharmaceuticals Inc. (RYTM, $12.48, NEUTRAL) INVESTMENT RATING AND PRICE TARGET HISTORY Tryp Therapeutics, Inc. Rating History as of 08/25/2021 powered by: BlueMatrix 1.00 0.90 0.80 0.70 0.60 0.50 0.40 0.30 Oct 2018 Jan 2019 Apr 2019 Jul 2019 Oct 2019 Jan 2020 Apr 2020 Jul 2020 Oct 2020 Jan 2021 Apr 2021 Jul 2021 B=Buy N=Neutral S=Sell D=Drop Coverage I=Initiate NR=Not Rated Rhythm Pharmaceuticals Inc. Rating History as of 08/25/2021 powered by: BlueMatrix 40 35 30 25 20 15 10 Oct 2018 Jan 2019 Apr 2019 Jul 2019 Oct 2019 Jan 2020 Apr 2020 Jul 2020 Oct 2020 Jan 2021 Apr 2021 Jul 2021 I:B:$43.00 03/13/19 B:$60.00 01/27/21 N:NA 08/04/21 B=Buy N=Neutral S=Sell D=Drop Coverage I=Initiate NR=Not Rated Michael Higgins 212.409.2074 Tryp Therapeutics, Inc. (TRYPF) Page 44