VistaGen Therapeutics Company Presentation

www.vistagen.com 23 Oral Atypical Antipsychotics • Often do not work; slow to work – Initial ADT effective in 1 of 3 patients – May take 4 to 6 weeks or more for antidepressant effects • Significant potential side effects – Anxiety, sexual dysfunction, insomnia, dizziness, nausea and vomiting, headache, sweating Oral Antidepressants • Often do not work – Only ca. 20% of patients respond to augmentation • Significant potential side effects – Weight gain, stomach pain, tiredness, dizziness, tardive dyskinesia, headache, nervousness, restlessness Current Standard of Care for MDD is Inadequate

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