VistaGen Therapeutics Company Presentation

www.vistagen.com 27 PH10 Dose HAM D Score P (PH10 vs Placebo) Cohen’s D (Effect Size) 3.2 P g (Low Dose) 16.3 .101 0.74 6.4 P g (High Dose) 17.8 .022 0.95 Placebo 10.9 PH10 Published Phase 2A MDD Study (n = 30) Microgram doses of PH10 neuroactive nasal spray improved MDD symptoms with rapid-onset efficacy (n = 30) Hamilton Depression (HAM D) Score Reduction From Baseline Monti, L., Nicolini, H., Liebowitz, M., & Hanover, R. (2019). “A Placebo Controlled Trial of PH10: Test of a New Rapidly Acting Intranasally Administered Antidepressant.” Br J Phar Med Res 4(6): 2157-2168.