VistaGen Therapeutics Company Presentation

www.vistagen.com 32 L- 7-CI-KYNA (full antagonist) Classic channel-blocking antagonists: Ketamine Lanicemine Phencyclidine AV-101 Oral Prodrug (4-Cl-KYN) AV-101 ActiveMetabolite (7-Cl-KYNA) Activated Astrocytes AV-101’s Mechanism of Action 4-Cl-KYN (prodrug) o 7-Cl-KYNA (active metabolite)